The Wellness Zone Podcast

Obesity and Aging

Have you ever wondered why centenarians—those remarkable individuals who live to 100 or beyond—are almost never obese? It’s not just a coincidence. Obesity is far more than a number on the scale; it’s a chronic inflammatory condition that speeds up aging and steals away your healthspan—the precious years you spend vibrant, active, and free from disease

Alzheimers Disease & Your Metabolism

There’s no approved drug to treat Alzheimer’s. But your diet can play a crucial role in prevention. Reducing insulin resistance may be one of the most powerful ways to protect your brain. That’s where Metabolic Engineering® comes in. In this episode, join Mary Perry and me to learn how this groundbreaking dietary approach can help lower your risk of cognitive decline and keep your brain healthier for years to come.

Can Ultra-Processed Foods Ever Be Healthy?

Ultra-processed foods often get a bad rap—and for good reason.
But what if we could re-engineer foods we love—like pasta, bread, and pastries—to not only keep their nutrients intact but also activate natural pathways that reduce hunger and inflammation caused by obesity?
Well, we can. It’s called Zone Foods, and it’s not science fiction—it’s science.

GLP-1 Drugs and AMPK Activation

GLP-1 drugs are often hailed as ‘miracle treatments’. But what makes them effective isn’t magic; it’s the activation of AMPK. This same metabolic pathway can be naturally activated through diet. Dr. Barry Sears and Maruy Perry dive into how this works and why AMPK might be the key to unlocking better health with less of a need for medication.

Biological vs Chronological Aging

How old are you, really? While your chronological age is just a number, your biological age reveals the true state of your body’s health. In this episode of the Wellness Zone, Dr. Barry Sears and Mary Perry explore the intriguing science of epigenetics—what switches our genes on or off—and how it impacts aging.

Expanding Lifespan & Increasing Healthspan

In this episode of The Wellness Zone podcast, Dr. Barry Sears and Mary Perry break down how your metabolism plays a key role in not just living longer, but living better. Tune in to discover the science behind improving your quality of life, and how small changes today can set you up for a healthier future.

The Three Stages of Metabolic Engineering

In this episode of the Wellness Zone Podcast, Dr. Barry Sears and Mary Perry, Director of Clinical Trials, explain the three stages of Metabolic Engineering, using a rocket analogy to break it down. Stage one is a calorie-restricted diet, like the Zone diet, to activate AMPK. Stage two involves omega-3s to reduce inflammation, and stage three introduces polyphenols to ensure a smooth transition to the Zone. Together, these stages set you on the path to a longer, healthier life.

The History of Wonder Drugs

From ancient willow bark to modern aspirin, all the way to today’s GLP-1, we'll explore how these mighty remedies have evolved. And guess what? They all share a secret superpower: activating AMPK!

Menopause And The Diet

When you think of menopause, diet might not be the first thing that comes to mind—but it should be. The symptoms of menopause are deeply intertwined with the metabolic shifts occurring in your body.

Managing ADHD with Metabolic Engineering

Today, we’re diving into a groundbreaking topic—Managing ADHD with Metabolic Engineering. While Metabolic Engineering isn’t a cure for ADHD, it can significantly enhance the effectiveness of ADHD medications. How? Both Metabolic Engineering and these medications activate a key enzyme called AMPK. When AMPK is activated, your brain’s neurotransmitters can perform at their best, leading to better focus and control. Tune in to learn how you can optimize your brain health and improve your ADHD management.