The Wellness Zone Podcast

How Poor Sleep Wrecks Your Metabolism (and How to Fix It)

When you’re awake, your body faces constant wear and tear. Sleep, however, is your body’s prime time for repair, resetting your metabolic processes and preparing you for the challenges of the day. Join Dr. Barry Sears and Mary Perry as they explore the critical connection between sleep quality and metabolic health. 

Polyphenols Explained: How They Affect Your Genes and Health

Polyphenols do more than just give fruits and vegetables their vibrant colors—they have the potential to influence your genes. That’s right, the food you eat can literally turn certain genes on or off. But how does this work? It all comes down to AMPK, the master regulator of metabolism.

The Science of Athletic Performance: How Energy, Focus & Metabolism Shape Success

The Metabolic Way to Improve Athletic Performance | Dr. Barry Sears
What’s the secret to peak athletic performance? It all comes down to two key factors: energy production and focus.
Join Dr. Barry Sears as he explains how Metabolic Engineering can give athletes the edge they need to perform at their

Can You Control Addictive Behavior with Diet?

GLP-1 drugs are now being used to treat addiction. But while GLP-1 drugs can be powerful, they come with serious side effects. The good news? You can achieve similar benefits naturally through Metabolic Engineering®, which is also based on calorie restriction—but designed for long-term health.

Microplastics Are Everywhere—And They Might Be Destroying Your Brain

From the water you drink to the food you eat, these tiny plastic particles are nearly impossible to avoid. Tune in to learn what you can do to minimize your exposure and protect your health—plus how all this relates back to your metabolism.

Obesity and Aging

Have you ever wondered why centenarians—those remarkable individuals who live to 100 or beyond—are almost never obese? It’s not just a coincidence. Obesity is far more than a number on the scale; it’s a chronic inflammatory condition that speeds up aging and steals away your healthspan—the precious years you spend vibrant, active, and free from disease

Alzheimers Disease & Your Metabolism

There’s no approved drug to treat Alzheimer’s. But your diet can play a crucial role in prevention. Reducing insulin resistance may be one of the most powerful ways to protect your brain. That’s where Metabolic Engineering® comes in. In this episode, join Mary Perry and me to learn how this groundbreaking dietary approach can help lower your risk of cognitive decline and keep your brain healthier for years to come.

Can Ultra-Processed Foods Ever Be Healthy?

Ultra-processed foods often get a bad rap—and for good reason.
But what if we could re-engineer foods we love—like pasta, bread, and pastries—to not only keep their nutrients intact but also activate natural pathways that reduce hunger and inflammation caused by obesity?
Well, we can. It’s called Zone Foods, and it’s not science fiction—it’s science.

GLP-1 Drugs and AMPK Activation

GLP-1 drugs are often hailed as ‘miracle treatments’. But what makes them effective isn’t magic; it’s the activation of AMPK. This same metabolic pathway can be naturally activated through diet. Dr. Barry Sears and Maruy Perry dive into how this works and why AMPK might be the key to unlocking better health with less of a need for medication.

Biological vs Chronological Aging

How old are you, really? While your chronological age is just a number, your biological age reveals the true state of your body’s health. In this episode of the Wellness Zone, Dr. Barry Sears and Mary Perry explore the intriguing science of epigenetics—what switches our genes on or off—and how it impacts aging.